Nevoscope is a patented* skin examination microscope with three modes of illumination (transillumination, surface illumination and epiluminescence) for total illumination of the skin and subsurface structures.

The light source is a bright halogen lamp with variable intensity control. The light is channeled through a flexible optical guide to the ring light in the Nevoscope, where it is directed onto the skin for transillumination of the area of interest.

Special surface light fibers shine light on to the surface of the skin. The combination of simultaneous transillumination and surface illumination provides ‘No Oil Epiluminescence’ imaging of lesions.

The amount of surface light can be controlled to enhance the subsurface pigmentation.

TransLite Nevoscope showing the ring light for transillumination and the surface lights

The optical lenses are interchangeable for different magnification.


Transillumination is a technique whereby the light is directed into the skin such that the scattered light from the skin illuminates the lesion from within the skin. Transillumination is achieved by putting the Nevoscope directly in contact with the skin. Fiber optic light guides direct the light so that it uniformly illuminates the area of interest and the light is ‘focused’ under the skin. Transillumination light intensity can be controlled by a knob on the light source box.


Transillumination mode illumination of the skin

Light is directed into the skin from the side so that it is, effectively, focused under the area of interest. There is no surface light and no surface reflection to interfere with imaging of subsurface structures.


Surface illumination is achieved by four fiber light point sources shining on to the skin from within the TransLite Nevoscope. The light from the surface light sources is adjusted by rotating a knob located on the TransLite Nevoscope. A combination of both surface and transillumination are achieved by placing the Nevoscope on the skin and rotating the adjustment control for the surface lighting. Conventional surface illumination is achieved by raising the Nevoscope a few millimeters from the surface of the skin with a special spacer, so that the light from the ring of fibers in the Nevoscope shines directly onto the skin and uniformly illuminates it from all angles.


Surface mode illumination of the skin

Most of the light shining down on the surface of the skin is reflected. Very little light penetrates the surface and the image of the skin is dominated by the reflected light. Subsurface structures are obscured by the surface reflected light.


Surface and transillumination demonstrated by viewing lemon skin

On the left is a conventional image of the surface of the lemon obtained with surface lighting only. On the right is the transillumination image obtained with transillumination only. It shows the subsurface structure in the lemon peel that is not visualized with surface lighting. The region imaged is approximately 8 x 8 mm in size. High resolution and magnification images show round subsurface structures that are most likely oil pockets.


Epiluminescence imaging of a pigmented lesion with the Dermatoscope (left) and transillumination imaging with the Nevoscope (right)

The Dermatoscope image was obtained with oil and a face plate. The image resolution has been reduced to display these images faster for the web pages. Higher resolution images show better pigmentation details in both images.



The TransLite Nevoscope does ‘No Oil or Face Plate’ epiluminescence imaging by combining the transillumination and surface illumination in the device. This mode of operation has three advantages: (1) there is no oil on the surface to change the characteristics of the skin, and (2) there are no air bubbles on the skin, and (3) raised lesions can be visualized without compressing them.


Surface, Epiluminescence and Transillumination, demonstrated by viewing a skin wound approximately 4 mm in diameter

Epiluminescence without oil and face-plate is achieved by simultaneous Surface and Transillumination.



8410 Highway 90A, Suite 150, Sugar Land, TX 77478


 Tel: 281.240.3111, Fax: 281.240.3122, E-mail: [email protected]